It could be made in the fifties or take place in the fifties.

As for shows made in the fifties, I Love Lucy was pretty funny, and I loved Lucy and Ethel's crazy antics.

My favorite show that takes place in the fifties but was made after that time is M*A*S*H. Even though the show aired for eleven years, they managed to fit it into three years, which was how long the Korean War was. Even though the show took place in the fifties, a lot of the characters has seventies hairstyles.